polyendocrine metabolic ovarian syndrome

Polyendocrine metabolic ovarian syndrome (PMOS) is a proposed condition in which metabolic disturbances—particularly insulin resistance, obesity, and dyslipidemia—interact with ovarian endocrine dysfunction, leading to irregular menstrual cycles, anovulation, and infertility. It reflects the combined impact of systemic metabolic disease (often seen in polycystic ovary syndrome) and broader endocrine imbalances affecting the ovaries. Diagnosis involves evaluating hormonal profiles, glucose metabolism, and ovarian imaging, while treatment targets both metabolic control (diet, exercise, insulin‑sensitizing drugs) and reproductive hormone regulation (combined oral contraceptives, ovulation‑inducing agents). Views Nigeria